Audible gasps and applause broke out during the nail-biting vote when Sen. Lindsey Graham (S.C.), Ron Johnson (Wis.), John McCain (Ariz.), and Bill Cassidy (La.) announced that they would each vote down the skinny bill unless the House promises that it won't pass the measure as is.
Rep. Annie Kuster called the vote a "win for the American people who are exhausted of partisan politics getting in the way of real solutions". "And participating insurers are on track to have their best year in the marketplaces since they began in 2014, according to the nonpartisan Kaiser Family Foundation".
As the Senate dug in for what promised to be a rare all-night session to debate amendments, a consensus was emerging among Republicans that the skinny bill would be used as a mechanism to keep working on an Obamacare replacement and not an end in itself.
It was unclear whether Republicans had enough votes to push the measure through.
Even a last-minute attempt by Vice President Mike Pence to persuade McCain to vote for the bill failed.
Trump said that police departments should be tougher on undocumented immigrants who have committed violent crimes. "I find it hard to believe that we can sit here and vote on a bill that is going to hurt millions and millions of people in our country".
"I've stated time and time again that one of the major failures of Obamacare was that it was rammed through Congress by Democrats on a strict party-line basis without a single Republican vote", he said.
McCain calls on both parties to work together
Then a so-called "vote-a-rama" begins, opening the floodgates for all senators to introduce as many amendments as they want. In his remarks Friday, McConnell said it will be "interesting to see what [Democrats] suggest is the way forward".
President Donald Trump pumps his fist after speaking to law enforcement officials on the street gang MS-13, Friday, July 28, 2017, in Brentwood, N.Y.
McCain's vote was the one that kept everyone in suspense and he had held his decision close to his chest till the final minutes - telling reporters to "wait for the show".
Democrat Chuck Schumer said his party was relieved that millions of people would retain their healthcare.
He looked at McCain during his speech.
"When we passed Obamacare in 2009, it split us", he said, "It split us dramatically and it split us for years".
Stacked card at UFC 214 in Anaheim this weekend
But it all spiralled out of control in April 2015 when Jon Jones was arrested for his involvement in a hit-and-run incident. He's an easygoing family man, who's come close to an Olympic medal and now holds a UFC title, but has never beaten Jones .
Trump to talk on gang violence
In the years since, it has continued to grow and spread to the USA , where it is active among communities of Central Americans. On Thursday, two of the gang's reputed members were arrested in Hempstead for a killing in May in Flushing, Queens.
UFC 214 preview: 'Jones vs. Cormier 2'
He doesn't just beat his opponents; he breaks them, turns even the proudest, most ruthless fighters into quivering bowls of jelly. Submission wins over Neil Magney and Carlos Condit were backed up by a recent split decision victory against Jorge Masvidal.
Hassan calls for Democrats, Republicans to fix health care
But McCain , who helped kick off the " skinny repeal " process earlier this week, in the end drove the dagger through its heart. He urged a bipartisan approach that would "produce a bill that finally delivers affordable healthcare for the American people".
Apple May Skirt IPhone Tariffs as Foxconn Comes to the US
Walker said he would convene a special session of the Wisconsin Legislature to address the Foxconn incentive package . But this is the biggest deal Wisconsin has done in terms of a sweetener, so $3 billion, that's a lot of money.
Reince Priebus pushed out as Trump's chief of staff
Scaramucci was named the White House communications director a week ago after Sean Spicer resigned as press secretary. It is the same moderates-versus-conservatives split that doomed the Obamacare rollback.
McCain Votes No, Derails 'Skinny Repeal' In Marathon Session
Mitch McConnell's tactical brilliance in dealing with health-care legislation doesn't mean he has a strategy for actual success. He said even the most conservative members will be reluctant to comment because of the uncertainty of what's to come.